Shock Waves Induce Activity of Human Osteoblast-Like Cells in Bioactive Scaffolds
نویسندگان
چکیده
منابع مشابه
Shock waves induce activity of human osteoblast-like cells in bioactive scaffolds.
BACKGROUND Bone replacement is frequently needed in periodontal, orthopedic, and maxillofacial diseases. To avoid complications with autografts and allografts, artificial grafts (scaffolds) are candidates for stimulating bone regeneration after colonization with osteoblasts. Moreover, osteoblast activity can be induced by biological or physical stimulation. In this research, extracorporeal shoc...
متن کاملThree-dimensional, bioactive, biodegradable, polymer-bioactive glass composite scaffolds with improved mechanical properties support collagen synthesis and mineralization of human osteoblast-like cells in vitro.
In the past decade, tissue engineering-based bone grafting has emerged as a viable alternative to biological and synthetic grafts. The biomaterial component is a critical determinant of the ultimate success of the tissue-engineered graft. Because no single existing material possesses all the necessary properties required in an ideal bone graft, our approach has been to develop a three dimension...
متن کامل[Article] Key role of the expression of bone morphogenetic proteins in increasing the osteogenic activity of osteoblast-like cells exposed to shock waves and seeded on bioactive glass-ceramic scaffolds for bone tissue engineering
In this work, the role of shock-wave (SW)-induced increase of bone morphogenetic proteins (BMPs) in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a BMP antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experimental bioactive glass (CEL2) developed at the Politecnico di Torino, were produced by the ...
متن کاملFormation in Isolated Human Osteoblast-Like Cells
The effect of bradykinin on prostaglandin E 2 formation in cells from human trabecular bone has been studied. The cells responded to parathyroid hormone with enhanced cyclic AMP formation and were growing as cuboidal-shaped, osteoblast-like cells. In these isolated human osteoblast-like cells, bradykinin (1 #tool/l) caused a rapid (5 min) stimulation of prostaglandin E2 formation. This finding ...
متن کاملSpontaneous in vitro transformation of primary human osteoblast-like cells.
BACKGROUND Two new tumor-like cell lines were established which developed spontaneously in vitro from normal human primary osteoblast-like cells originating from non-oncogenic bone surgery. MATERIALS AND METHODS The tumor cell properties studied included morphology, proliferation characteristics in normal and low-serum media, and anchorage-independent growth in soft agarose. RESULTS AND CON...
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ژورنال
عنوان ژورنال: Journal of Trauma: Injury, Infection & Critical Care
سال: 2010
ISSN: 0022-5282
DOI: 10.1097/ta.0b013e3181b28a8c